Differential diagnosis of benign and malignant prostate tumors by polarization-singular Mueller matrix microscopy of polycrystalline blood films

Authors

  • L. Tryfonyuk Національний університет водного господарства та природокористування
  • O.H Ushenko Чернівецький національний університет імені Ю. Федьковича
  • I.S. Davydenko ВДНЗ "Буковинський державний медичний університет
  • I.YU. Polyansʹkyy Чернівецький державний медичний інститут
  • O.I. Herasymenko Донецький національний медичний університет
  • K.M. Suloyev Дніпровський державний медичний університет

DOI:

https://doi.org/10.31649/1681-7893-2020-40-2-21-28

Keywords:

Mueller-matrix polarimetry, differential diagnosis

Abstract

The article presents the results of determining the possibilities of polarization-singular approach to improve the efficiency of Mueller-matrix polarimetry in the differential diagnosis of benign and malignant with varying degrees of differentiation of prostate tumors. The relationships between the characteristic values of the elements of the Mueller matrix and the polarization-singular L - states of microscopic images of histological sections of the biopsy of prostate tumors and polycrystalline blood films were determined. The technique of experimental determination of distributions of characteristic values of Mueller-matrix images is developed and tested. Statistical criteria for rapid differential diagnosis of histological sections of prostate adenoma and adenocarcinoma with different degrees of differentiation were determined. The operational characteristics (sensitivity, specificity, accuracy) of the diagnostic power of the singular polarimetry method are determined.

Author Biographies

L. Tryfonyuk, Національний університет водного господарства та природокористування

к.т.н., доц.

O.H Ushenko, Чернівецький національний університет імені Ю. Федьковича

д.ф-м.н., проф.

I.S. Davydenko, ВДНЗ "Буковинський державний медичний університет

д.м.н., проф.

I.YU. Polyansʹkyy, Чернівецький державний медичний інститут

д.м.н., проф.

O.I. Herasymenko, Донецький національний медичний університет

д.м.н., проф.

K.M. Suloyev, Дніпровський державний медичний університет

к.м.н., доц.

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Published

2021-09-01

How to Cite

[1]
L. . Tryfonyuk, O. Ushenko, I. Davydenko, I. Polyansʹkyy, O. Herasymenko, and K. Suloyev, “Differential diagnosis of benign and malignant prostate tumors by polarization-singular Mueller matrix microscopy of polycrystalline blood films”, Опт-ел. інф-енерг. техн., vol. 40, no. 2, pp. 21–29, Sep. 2021.

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Section

Biomedical Optical And Electronic Systems And Devices

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