DEVELOPMENT AND TESTING OF A NEW VERSION OF PHOTODYNAMIC THERAPY OF TUMORS METHOD OF USING LASER SCANNING DEVICE

Authors

  • O. M. Chepurna PMVP "Photonics Plus"
  • I. O. Shton Institute of Experimental Pathology
  • V. S. Voitsekhovych Institute of Physics, National Academy of Sciences of Ukraine
  • V. V. Kholin PMVP "Photonics Plus"
  • Ronald U. Rovira Vinnytsia National Technical University
  • O. S. Kaminskyi Vinnytsia National Technical University
  • M. F. Hamaliia Institute of Experimental Pathology

Keywords:

Photodynamic therapy, a device for irradiation of tumors, scanning laser radiation

Abstract

The work proposed and approved version of the method of photodynamic therapy of tumors, which is a laser beam scanning the tumor small cross section, which moves in the selected area with a certain delay in every point, with rescanning area starting from the same starting point. Experimental verification method pereschepleniy in tumor-bearing mice showed that the efficiency of inhibition of tumor growth, he yielded to normal continuous exposure method is only 20%, while the applied dose was less than 400 times.

Author Biographies

O. M. Chepurna, PMVP "Photonics Plus"

graduate student of "Computer and Information Technology in instrument," engineer

I. O. Shton, Institute of Experimental Pathology

trans. Laboratory engineer quantum Nanobiology

V. S. Voitsekhovych, Institute of Physics, National Academy of Sciences of Ukraine

Ph.D., Researcher

V. V. Kholin, PMVP "Photonics Plus"

Director

Ronald U. Rovira, Vinnytsia National Technical University

Postgraduate Department of Physics and Photonics

O. S. Kaminskyi, Vinnytsia National Technical University

Senior Engineer Department of Physics and Photonics

M. F. Hamaliia, Institute of Experimental Pathology

Dr. Sci., Head of the Laboratory of Quantum Nanobiology

References

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2. Патент RU 2438733 Способ фотодинамической терапии онкологических заболеваний / Иванов А.П., Ньунг Ч.Х., Тхань Н.К., Барун В.В.// МПК А61/N06.
3. Allison R.R., Moghissi K. Oncologic photodynamic therapy: clinical strategies that modulate mechanisms of action // Photodiagnosis Photodyn. Ther. – 2006. – Vol. 10, № 4. – P. 331-341.
4. Pass HI. Photodynamic therapy in oncology: mechanism and clinical use. // J Natl. Cancer Inst. – 1993. – Vol.85, №6. – P. 443-456.
5. Патент RU 2169015, Способ фотодинамической терапии злокачественных опухолей/ Харнас С.С., Торшина Н.Л., Лужков Ю.М., Ворожцов Г.Н., Посыпанова А.Н. Волкова А.И.//МПК А 61 N 5/06, публ. Бюл. 2001, № 17.

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How to Cite

[1]
O. M. Chepurna, “DEVELOPMENT AND TESTING OF A NEW VERSION OF PHOTODYNAMIC THERAPY OF TUMORS METHOD OF USING LASER SCANNING DEVICE”, Опт-ел. інф-енерг. техн., vol. 27, no. 1, pp. 128–131, Aug. 2014.

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Section

Biomedical Optical And Electronic Systems And Devices

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